Myocardial Lipid and Creatine of Heart Failure on MRS

CompletedOBSERVATIONAL
Enrollment

71

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

December 31, 2016

Study Completion Date

December 31, 2016

Conditions
Myocardial Lipid
Interventions
OTHER

Proton (1H-) magnetic resonance (MR) spectroscopy

PRESS localized 1D MRS sequence was used on a 3-T MR system. The lipid resonances will be analyzed using the LC-Model algorithm, and a Cramer-Rao lower bound (CRLB) threshold of 50% was used as quality control. Resonances of fatty acid (FA, lipid resonances δ 0.9, 1.3 and 1.6 ppm) and polyunsaturated fatty acid (PUFA, lipid resonance δ 2.1 and 2.3, 2.8, 5.3 ppm) will be evaluated on MRS, with ratios normalized with total TG value.

Trial Locations (1)

333

Department of Radiology, Chang Gung Memorial Hospital, Guishan

All Listed Sponsors
lead

Chang Gung Memorial Hospital

OTHER

NCT02378402 - Myocardial Lipid and Creatine of Heart Failure on MRS | Biotech Hunter | Biotech Hunter