182
Participants
Start Date
February 28, 2015
Primary Completion Date
February 28, 2017
Study Completion Date
June 30, 2017
Oral alkalinization (Potassium citrate, Allopurinol)
"Eligible patients, who fulfilled the study criteria, will be instructed For; Oral alkalinization therapy~* Potassium citrate 20 mEq three times daily~* Hyperuricosuric patients (24-hours urine uric acid more than 750 mg/day in male and more than 650mg/day in females) will receive:~Allopurinol, a competitive inhibitor of xanthine oxidase, in a dose of 300 mg daily."
Life style modification
"Eligible patients, who fulfilled the study criteria, will be also instructed for;~Adequate fluid intake in order to maintain urine volume between 2-3 L per day."
Dietary recommendations (decrease purine rich diet as red meat and fish, increase vegetables)
Eligible patients, who fulfilled the study criteria and they are hyperuricosuric (24-hours urine uric acid more than 750 mg/day in male and more than 650mg/day in females) will be also instructed for; Dietary modification will be advised in the form of decrease purine rich diet as red meat and fish, increase vegetables.
Urology and Nephrology Center, Al Mansurah
Mansoura University
OTHER