"It is a Real The First Baby Of Autologous Stem Cell Therapy in Premature Ovarian Failure"

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

112

Participants

Timeline

Start Date

March 31, 2012

Primary Completion Date

December 31, 2014

Study Completion Date

December 31, 2014

Conditions
Premature Ovarian Failure
Interventions
BIOLOGICAL

Stem cell

Out of 112 high risk patients for POF diagnosis was established in 10 cases. Endometrial fractional biopsy was taken, stained with H\&E stain and by Immunohistochemical (IH) staining by stem cell marker OCT4. IH expression of stem cell was evaluated before and after transplantation according to Edessy Stem Cell Scoring (ESS). After laparoscopic injection of stem cell sample in the ovaries, participants were followed up monthly for a period of one year by hormonal (FSH, LH and E2), clinical (resuming menstruation and pregnancy), US (folliculometry), histopathological (HP), and IH expression of stem cell (stem cell positivity and scoring according to ESS).

Trial Locations (1)

Unknown

Al Azhar University, Cairo

All Listed Sponsors
lead

Al-Azhar University

OTHER

NCT02372474 - "It is a Real The First Baby Of Autologous Stem Cell Therapy in Premature Ovarian Failure" | Biotech Hunter | Biotech Hunter