Drug-drug Interaction Study of GSK1278863 With Pioglitazone, Rosuvastatin and Trimethoprim in Healthy Adult Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

February 11, 2015

Primary Completion Date

August 12, 2015

Study Completion Date

August 12, 2015

Conditions
Anaemia
Interventions
DRUG

GSK1278863 25 mg Tablet

A round, biconvex, white film coated tablet to be taken orally in the fasted state in the morning

DRUG

Pioglitazone 15 mg Tablet

"White to off-white, round, convex, non scored tablet with ACTOS on one side, and 15 on the other, to be taken orally in the fasted state in the morning"

DRUG

Rosuvastatin 10 mg Tablet

"Pink, round, biconvex, coated tablets. Debossed CRESTOR and 10 on one side, to be taken orally in the fasted state in the morning"

DRUG

Trimethoprim 100 mg Tablet

"White, round, scored, convex tablet, debossed 93 above the score and debossed 2159 below the score on one side and plain on the other, to be taken orally as two tablets once in the morning and once in the evening"

Trial Locations (1)

66211

GSK Investigational Site, Overland Park

Sponsors

Lead Sponsor

All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY

NCT02371603 - Drug-drug Interaction Study of GSK1278863 With Pioglitazone, Rosuvastatin and Trimethoprim in Healthy Adult Volunteers | Biotech Hunter | Biotech Hunter