Oral Apixaban (Eliquis) Versus Enoxaparin (Lovenox) for Thromboprophylaxis in Women With Suspected Pelvic Malignancy

PHASE2CompletedINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

April 28, 2015

Primary Completion Date

June 30, 2019

Study Completion Date

June 30, 2019

Conditions
Gynecologic CancerVenous Thromboembolism
Interventions
DRUG

Oral apixaban

To evaluate the incidence of major bleeding (including CRNM bleeding) events in women undergoing surgery for gynecologic cancer with apixaban 2.5 mg BID compared to current standard of care, subcutaneous enoxaparin 40 mg QD for 28 days post surgery.

DRUG

Subcutaneous enoxaparin

To evaluate the incidence of major bleeding (including CRNM bleeding) events in women undergoing surgery for gynecologic cancer with apixaban 2.5 mg BID compared to current standard of care, subcutaneous enoxaparin 40 mg QD for 28 days post surgery.

Trial Locations (2)

80045

University of Colorado Denver, Aurora

90089

University of Southern California Keck School of Medicine, Los Angeles

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

University of Colorado, Denver

OTHER