Inflammation and Coronary Endothelial Function

PHASE2CompletedINTERVENTIONAL
Enrollment

111

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

August 1, 2020

Study Completion Date

September 1, 2020

Conditions
Coronary Artery Disease
Interventions
DRUG

Methotrexate

Administered to determine the effect of anti-inflammatory agents on coronary and systemic endothelial function in patients with coronary artery disease

DRUG

Colchicine

Administered to determine the effect of anti-inflammatory agents on coronary and systemic endothelial function in patients with coronary artery disease.

DRUG

Placebo

Prepared by Johns Hopkins Investigational Drug Service to mimic methotrexate and colchicine.

Trial Locations (1)

21287

Johns Hopkins Hospital, Baltimore

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Johns Hopkins University

OTHER

NCT02366091 - Inflammation and Coronary Endothelial Function | Biotech Hunter | Biotech Hunter