A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor

PHASE1TerminatedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

January 9, 2015

Primary Completion Date

March 15, 2018

Study Completion Date

March 15, 2018

Conditions
Head and Neck Squamous Cell CarcinomaNon-small Cell Lung CancerTriple Negative Breast CancerColorectal CarcinomaGlioblastoma Multiforme
Interventions
DRUG

ABBV-221

ABBV-221 will be given either every 3 weeks or 2 weeks on, 1 week off or weekly dosing by intravenous infusion approximately over 30 minutes to 3 hours. This is a dose escalation study, therefore the dose of ABBV-221 will change throughout the study.

Trial Locations (5)

28040

Fundacion Jimenez Diaz, Madrid

28050

Hosp Univ Madrid Sanchinarro, Madrid

78229

South Texas Accelerated Research Therapeutics, San Antonio

02114

Massachusetts General Hospital, Boston

02215

Dana-Farber Cancer Institute, Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AbbVie

INDUSTRY