Liberal Versus Restrictive Use of Dobutamine in Cardiac Surgery

PHASE3CompletedINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

February 28, 2015

Primary Completion Date

February 29, 2016

Study Completion Date

June 30, 2018

Conditions
Cardiac Output, LowCoronary Disease
Interventions
DRUG

Liberal dobutamine protocol

All patients will receive dobutamine at the cardiopulmonary bypass weaning.

DRUG

Restrictive dobutamine protocol

Patients will receive dobutamine during the first 8 hours after cardiopulmonary bypass weaning only if they have a cardiac index of ≤ 2.5L/min/m2 and at least one sign of tissue hypoperfusion: ScvO2 ≤ 70% and / or urine output \< 2 mL/Kg/h despite adequate fluid replacement.

Trial Locations (1)

05403000

Heart Institute, São Paulo

All Listed Sponsors
lead

University of Sao Paulo

OTHER

NCT02361801 - Liberal Versus Restrictive Use of Dobutamine in Cardiac Surgery | Biotech Hunter | Biotech Hunter