NCT02361658View on ClinicalTrials.gov

Optic Nerve Sheath Diameter (ONSD) With the Raised PCO2 and Internal Jugular Venous Occlusion

CompletedOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

May 31, 2017

Study Completion Date

May 31, 2017

Conditions
Elevated Intracranial Pressure (ICP)
Interventions
OTHER

Ultrasonographic of the optic nerve sheath diameter

On both eyes of all subjects in supine position by two investigators.

OTHER

RespirAct™

Carbon dioxide Manipulation by RespirAct™ sequential gas delivery breathing circuit at each CO2 levels (normocapnia, Hypercapnia I and II and hypocapnia).

OTHER

Neck collar

Internal jugular compression using a Neck collar will be applied at each CO2 levels (normocapnia, Hypercapnia I and II and hypocapnia) and ONSD measurements will be done before and after the collar.

Trial Locations (1)

M5T2S8

Toronto Western Hospital, Toronto

All Listed Sponsors
collaborator

University Health Network, Toronto

OTHER

lead

Lashmi Venkatraghavan

OTHER

NCT02361658 - Optic Nerve Sheath Diameter (ONSD) With the Raised PCO2 and Internal Jugular Venous Occlusion | Biotech Hunter | Biotech Hunter