Study Investigating the Effects of JNJ-54861911 on Amyloid-beta Processing in Cerebrospinal Fluid (CSF) and Plasma in Japanese Participants Asymptomatic at Risk for Alzheimer Dementia

PHASE1CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

February 16, 2015

Primary Completion Date

September 8, 2015

Study Completion Date

September 8, 2015

Conditions
Alzheimer's Disease
Interventions
DRUG

JNJ-54861911, 10 mg

JNJ-54861911, 10 mg (2\*5 mg tablet) orally once daily for 4 weeks.

DRUG

JNJ-54861911, 50 mg

JNJ-54861911, 50 mg (2\*25 mg tablet) orally once daily for 4 weeks.

DRUG

Placebo

Placebo matching to JNJ-54861911 tablet orally once daily for 4 weeks.

Trial Locations (2)

Unknown

Fukuoka

Tokyo

Sponsors
All Listed Sponsors
lead

Janssen Pharmaceutical K.K.

INDUSTRY