NCT02356653View on ClinicalTrials.gov

Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

December 31, 2013

Primary Completion Date

January 31, 2027

Study Completion Date

January 31, 2030

Conditions
LeukemiaInborn Errors of MetabolismBone Marrow Failure SyndromesImmunodeficienciesImmunodysregulation Polyendocrinopathy Enteropathy X-linked Syndrome
Interventions
DEVICE

Transplant of stem cells with CD3+/CD19+ depletion (CliniMACs)

Processing of stem cells using the CliniMACs device to selectively deplete specific T cells to decrease risk of graft versus host disease when using donor stem cells which are not fully matched.

Trial Locations (1)

19104

RECRUITING

Children's Hospital of Philadelphia, Philadelphia

All Listed Sponsors
lead

Children's Hospital of Philadelphia

OTHER