Comparative Evaluation of Two Different Radiosurgery

NACompletedINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

December 15, 2014

Primary Completion Date

June 30, 2020

Study Completion Date

July 31, 2021

Conditions
Metastases to Brain
Interventions
RADIATION

Radiosurgery with Gamma Knife Perfexion

Gamma Knife Radiosurgery is a very precise form of therapeutic radiology. Even though it is called surgery, a Gamma Knife procedure does not involve actual surgery but it uses 192 isocentric beams of highly-focused gamma rays (60-Co) to treat small to medium size lesions. Minimum beam size is 4 mm. This procedure is frame based.

RADIATION

Linac-based Radiosurgery with EDGE

EDGE linear accelerator from Varian (Varian, Palo Alto, USA) is a C-arm machine specifically developed for radiosurgery frameless treatment. The characteristics of this linac are a high level of precision and the possibility to include multiple positioning systems for stereotactical treatments, among which Cone Beam CT (CBCT), the Optical Surface Monitoring System (OSMS), and Calypso.

Trial Locations (1)

20089

Istituto Clinico Humanitas, Rozzano

All Listed Sponsors
lead

Istituto Clinico Humanitas

OTHER

NCT02355613 - Comparative Evaluation of Two Different Radiosurgery | Biotech Hunter | Biotech Hunter