Measuring Lung Pressures in Critically Ill Children Who Are on Mechanical Ventilation

Active, not recruitingOBSERVATIONAL
Enrollment

55

Participants

Timeline

Start Date

February 28, 2014

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Transpulmonary PressurePressure.Rate ProductGuide to Mechanical Ventilator ManagementExtubation Readiness
Interventions
DEVICE

Transpulmonary Pressure measurement

Transpulmonary pressure measurements are done by placing a catheter (often combined with a feeding tube) into the esophagus of a patient. Intermittently, the esophageal pressure is measured by inflating a small balloon on this catheter. The resulting esophageal pressure is accepted as representing the pleural pressure. The difference between this pressure and the airway pressure is the transpulmonary pressure and PEEP is raised or lowered to make this value zero so that the forces distending the alveoli are just balanced with the natural elasticity of the lung which wants to collapse the alveoli.

Trial Locations (1)

90027

Children's Hospital Los Angeles, Los Angeles

All Listed Sponsors
lead

Children's Hospital Los Angeles

OTHER

NCT02354365 - Measuring Lung Pressures in Critically Ill Children Who Are on Mechanical Ventilation | Biotech Hunter | Biotech Hunter