A Study to Assess Inflammation in Rheumatoid Arthritis Using Molecular Imaging Techniques

PHASE1TerminatedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

August 12, 2015

Primary Completion Date

October 26, 2016

Study Completion Date

October 26, 2016

Conditions
Arthritis, Rheumatoid
Interventions
OTHER

Gadobutrol

Gadobutrol is a solution for intravenous (IV) injection in prefilled syringe/cartridge with a unit dose strength of 1.0 millimole (mmol)/mL solution, and will be administered at up to 0.1mmol/kg.

OTHER

18F-FDG

18F-FDG is a solution for IV injection in multidose vial, maximum 10 mL with unit dose strength of 160 megabecquerel (MBq) at maximum.

OTHER

18F-GE-180

18F-GE-180 solution for IV injection in 10mL glass vial. Patients will receive a maximum activity of 195 MBq in a maximum volume of 10 mL (bolus) of 18F-GE-180, containing not more than 2 microgram (mcg)/mL 18F-GE-180 (20 mcg for a 10 mL dose).

Trial Locations (2)

CB2 0QQ

GSK Investigational Site, Cambridge

CB2 2GG

GSK Investigational Site, Cambridge

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Cambridge University Hospitals NHS Foundation Trust

OTHER

lead

GlaxoSmithKline

INDUSTRY

NCT02350426 - A Study to Assess Inflammation in Rheumatoid Arthritis Using Molecular Imaging Techniques | Biotech Hunter | Biotech Hunter