327
Participants
Start Date
January 31, 2015
Primary Completion Date
August 31, 2018
Study Completion Date
August 31, 2018
AV2
"The virucide AV2 consists of a spray. It is a mixture of natural essential oil components (Carvone, Eugenol, Geraniol, Nerolidol) in equal volumes diluted 50% in olive oil (Olea europaea).~It is administered as a topical spray to the cervix while the subject is in the lithotomic position and fitted with a speculum. The manual spray applicator is positioned inside the anterior of the vagina and two pumps are applied. Each pump delivers 100 microliters of the solution."
Placebo
"The placebo consists of 10% lemon (citrus limon) and 10% lime (citrus aurantifolia) in 80% olive oil.~It is administered as a one time (2 puffs) topical spray of 100 microliters on the cervix."
Centre de Santé Lisungi, Kinshasa
University of Kinshasa
OTHER
University Hospital, Antwerp
OTHER
Jean-Pierre Van geertruyden
OTHER