Effect of Renal Denervation in End Staged Renal Disease With Resistant Hypertension

PHASE3UnknownINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

September 30, 2014

Primary Completion Date

August 31, 2015

Study Completion Date

October 31, 2018

Conditions
Hypertension
Interventions
PROCEDURE

Renal sympathetic denervation

"In the experimental arm, Intervention is renal sympathetic denervation using Symplicity® system (Medtronic Ardian Inc, Mountain View, CA, USA) and antihypertensive medications previously prescribed~1. After femoral puncture guiding catheter is engaged in renal artery~2. Symplicity radiofrequency ablation catheter is inserted into renal artery and by circular sequence, from distal to proximal portion, ablation energy is applied to the wall of renal artery~3. 4-5 ablations are applied in each renal artery.~In the sham comparator, intervention is renal angiogram and continue antihypertensive medications previuosly decribed"

Trial Locations (4)

301-723

RECRUITING

Daejon St. Mary's Hospital, Daejeon

301-721

RECRUITING

Chungnam National University, Daejeon

790-825

RECRUITING

Pohang St. Mary's Hospital, Pohang

137-701

RECRUITING

Seoul St. Mary's Hospital, Seoul

Sponsors
All Listed Sponsors
collaborator

Daewoong Pharmaceutical Co. LTD.

INDUSTRY

collaborator

Daiichi Sankyo Korea Co., Ltd.

INDUSTRY

lead

Seoul St. Mary's Hospital

OTHER