An Efficacy and Safety Study of CNTO1959 (Guselkumab) in the Treatment of Participants With Generalized Pustular Psoriasis or Erythrodermic Psoriasis

PHASE3CompletedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

January 19, 2015

Primary Completion Date

December 4, 2015

Study Completion Date

November 2, 2018

Conditions
Pustular Psoriasis
Interventions
DRUG

Guselkumab

"Participants will receive 50 milligram (mg) guselkumab subcutaneously at Weeks 0, 4 and 12. At Week 16 through the study end (Week 52) participants who are defined Very much improved or Much improved in Clinical Global Impression (CGI) will continue to receive guselkumab 50 mg every 8 weeks from Week 20 to the study end (Week 52). At each visit timing from Week 20, participants who are defined No change or Worsened in CGI will receive guselkumab 100 mg and continue 100 mg every 8 weeks dosing until the study end (Week 52). Participants who are defined Minimally improved in CGI will also receive guselkumab 100 mg only if the investigator considers that it is necessary."

Trial Locations (20)

Unknown

Asahikawa

Fukuoka

Gifu

Izumo

Kawasaki

Kita-Gun

Kochi

Kurume

Matsumoto

Miyagi

Morioka

Nagoya

Sapporo

Shimotsuke

Tokushima

Tokyo

Tsu

Tsukuba

Ube

Yokosuka

Sponsors
All Listed Sponsors
lead

Janssen Pharmaceutical K.K.

INDUSTRY