Involvement of Steatosis-induced Glucagon Resistance in Hyperglucagonaemia

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

January 31, 2016

Study Completion Date

January 31, 2016

Conditions
Non-alcoholic Fatty Liver Disease
Interventions
PROCEDURE

Liver biopsy

One ultrasound guided liver biopsy

OTHER

Pancreatic clamp

I.v. infusions of somatostatin and insulin (basal rate) for will be adminstered for 3 hours. Glucagon will administered for 3 hours in total with infusion rates at a basal and a high physiological rate for 1.5 hours each.

Trial Locations (1)

2900

Center for Diabetes Research, Gentofte Municipality

All Listed Sponsors
collaborator

The Novo Nordisk Foundation Center for Basic Metabolic Research

OTHER

lead

University Hospital, Gentofte, Copenhagen

OTHER

NCT02337660 - Involvement of Steatosis-induced Glucagon Resistance in Hyperglucagonaemia | Biotech Hunter | Biotech Hunter