Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

August 31, 2014

Primary Completion Date

March 31, 2015

Study Completion Date

January 31, 2016

Conditions
Precursor T-Cell Lymphoblastic Leukemia-LymphomaLeukemia, Myeloid, AcuteImmune Deficiency DiseaseBone Marrow Failure SyndromesOpportunistic InfectionsGraft vs Host Disease
Interventions
BIOLOGICAL

CD45RA-depleted peripheral blood mononuclear cells

Infusion of escalating doses of CD45RA-depleted donor-derived allogeneic peripheral blood mononuclear cells

Trial Locations (1)

117997

Federal Research Center for pediatric hematology, oncology and immunology, Moscow

All Listed Sponsors
lead

Federal Research Institute of Pediatric Hematology, Oncology and Immunology

OTHER

NCT02337595 - Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation | Biotech Hunter | Biotech Hunter