Mexiletine and Non Dystrophic Myotonias

PHASE3CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

June 30, 2011

Primary Completion Date

January 31, 2014

Study Completion Date

January 31, 2014

Conditions
Non-dystrophic MyotoniasParamyotonia CongenitaMyotonia Congenita
Interventions
DRUG

Mexiletine

"* Blisters of 10 capsules of 200 mg mexiletine hydrochloride.~* Patients will receive gradual dose of the treatment as it would be done in clinical practice.~* Mexiletine will be started at 200 mg / day (1 capsule to be taken at the beginning of the meal) and will be increased by 200mg every 3 days to reach a maximum of 600mg / day in 3 taken in 1 week.~* The duration of each treatment period is 18 days minimum (maximum 22 days)."

DRUG

placebo

Trial Locations (1)

75013

Groupe Hospitalier Pitié Salpetriere, Paris

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT02336477 - Mexiletine and Non Dystrophic Myotonias | Biotech Hunter | Biotech Hunter