2,022
Participants
Start Date
January 31, 2014
Primary Completion Date
June 30, 2017
Study Completion Date
June 30, 2017
Breath sampling for volatile marker detection
Acquisition of two exhaled breath samples of alveolar air to be analysed by GCMS and nanosensor technology
Upper endoscopy with biopsies
Upper endoscopy with proper biopsy work-up will be used for identification and stratification of gastric lesions as well as acquisition of biopsies for microbiota testing
Colonoscopy with biopsies or lesion removal when required
Colonoscopy with proper biopsy or polypectomy material work-up will be used for identification and stratification of colorectal lesions as well as acquisition of biopsies for microbiota testing
Plasma/serum sampling
Plasma/serum sampling will be used to obtain information for group stratification, e.g. H.pylori status determination
Faecal sample acquisition
Faecal samples will be obtained for faecal occult blood testing as well as microbiota analysis
Histological evaluation of the surgery material
The material obtained during surgery (stomach or colorectal) will be used for confirmation of the diagnosis in cancer groups. Surgery itself will be performed according to the clinical indications, and will not be extended (i.e. cannot be considered a study intervention)
University of Latvia, Riga
Lithuanian University of Health Sciences, Kaunas
Technion, Israel Institute of Technology
OTHER
Lithuanian University of Health Sciences
OTHER
Karolinska Institutet
OTHER
German Cancer Research Center
OTHER
Digestive Diseases Centre GASTRO
OTHER
Riga East Clinical University Hospital
OTHER_GOV
Academic Histology Laboratory (Latvia)
OTHER
JLM Innovation GmbH (Germany)
UNKNOWN
University of Latvia
OTHER