Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy

PHASE4CompletedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

February 29, 2016

Study Completion Date

April 30, 2016

Conditions
Gall Stone Disease
Interventions
DRUG

Lidocaine

Lidocaine intravenous 1.5mg/kg IV bolus at the time of induction followed by IV infusion @ 1.5 mg/kg/hr till the last suture.

DRUG

Esmolol

Esmolol intravenous bolus 0.5 mg/kg at the time of induction followed by infusion @ 5-15 microgram/kg/min till the last suture.

DRUG

Paracetamol

Inj. Paracetamol 1 gm IV at the time of induction

DRUG

Lidocaine

Inj. Xylocaine 2% 3 ml will be infiltrated in skin in all port sites prior to incision.

DRUG

Propofol

Inj. Propofol 2- 2.5 mg/kg will be given for induction

DRUG

Fentanyl

Inj fentanyl 1.5mg/kg will be given at the time of induction.

DRUG

Vecuronium

Inj Vecuronium 0.1mg/kg will be given at induction and for maintenance.

DRUG

Atropine

Inj Atropine 0.4 mg IV will be given for bradycardia (HR \< 50/min)

DRUG

Ephedrine

DRUG

Morphine

DRUG

Ketorolac

DRUG

Ondansetron

DRUG

Bupivacaine

Inj. Bupivacaine 0.25% 10 ml will be infiltrated at incision site after closure.

DRUG

Tramadol

Inj tramadol 50 mg IV will be given on SOS basis in ward.

DRUG

Neostigmine

50 mcg/kg for reversal of residual neuromuscular blockade

DRUG

Glycopyrrolate

10 mcg/kg with neostigmine

Trial Locations (1)

Unknown

BP Koirala Institute of Health Sciences, Dharān

All Listed Sponsors
lead

B.P. Koirala Institute of Health Sciences

OTHER

NCT02327923 - Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy | Biotech Hunter | Biotech Hunter