NCT02325713 - Relative Bioavailability Trial of Oral Dispersible Praziquantel Tablets in Healthy Volunteers | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

January 31, 2015

Study Completion Date

March 31, 2015

Conditions

Healthy

Interventions

DRUG

Oral dispersible tablet of praziquantel (ODT-PZQ)

Treatment A (test): ODT-PZQ (MSC1028703A) at a single dose of 40 milligram per kilogram (mg/kg) orally dispersed in water after meal.

DRUG

Cysticide

Treatment B (reference): Cysticide tablet at a single dose of 40 mg/kg will be given with water orally after a meal.

DRUG

ODT-PZQ

Treatment C1 (test): ODT-PZQ (MSC1028703A) at a single dose of 20 mg/kg orally dispersed in water after a meal.

DRUG

ODT-PZQ

Treatment C2 (test): ODT-PZQ (MSC1028703A) at a single dose of 60 mg/kg orally dispersed in water after a meal.

DRUG

ODT-PZQ

Treatment D1 (test): ODT-PZQ (MSC1028703A) at a single dose of 40 mg/kg orally dispersed in water without a meal.

DRUG

Cysticide

Treatment D2 (reference): Cysticide crushed tablets at a single dose of 40 mg/kg will be given with water orally after a meal.

Trial Locations (1)

Please contact the Merck KGaA Communication Center, Darmstadt

All Listed Sponsors

lead

Merck KGaA, Darmstadt, Germany

INDUSTRY