Endovascular Treatment of TAAA and Aortic Arch Aneurysms Using Fenestrated and Branched Stent Grafts

NARecruitingINTERVENTIONAL
Enrollment

370

Participants

Timeline

Start Date

November 30, 2013

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2033

Conditions
Aortic Aneurysm, ThoracoabdominalAortic Aneurysm, ThoracicAortic Dissection, Thoracoabdominal
Interventions
DEVICE

Endovascular treatment of Thoracoabdominal Aortic Aneurysm

"A TAAA is an abnormal enlargement (ballooning out) of the main artery (the aorta) and involves all or part of the aorta in your chest as well as all or part of the aorta in the abdomen. It also involves the part of the aorta where the arteries that bring blood to the liver, stomach and intestines and kidneys are attached.~This investigational procedure that is being studied uses stent-grafts (cylindrical fabric tubes (grafts), with metal springs (stents) attached). The stent-grafts are placed inside the aneurysmal (weakened) area of the aorta to re-line it. These customized stent-grafts have special branches attached to them or openings (called fenestrations) that are used to keep blood flowing to the arteries that supply the liver, stomach, intestines and kidneys. The investigational stent graft will be designed and custom-made specifically for your aneurysm."

DEVICE

Endovascular treatment of Aortic Arch Aneurysms

"An aortic arch aneurysm is an abnormal enlargement (ballooning out) of the main artery (the aorta). The ascending aorta and aortic arch is the first part of the vessel as it exits the heart and makes a turn around the area of the collar bone. This part of the aorta gives branches that supply the head, brain and arms.~The arch branch endovascular graft includes the main aortic arch portion and one to three cuffs (side branches) that allow the graft to be located in the aortic arch. The number of cuffs is decided based on the anatomy of your aneurysm. The arteries in the aortic arch are the innominate artery (Zone 0), left common carotid artery (Zone 1) and the left subclavian artery (Zone 2). These arteries supply the right arm and right side of the brain, the left side of the brain and the left arm, respectively."

Trial Locations (2)

10022

ACTIVE_NOT_RECRUITING

New York Presbyterian Hospital, New York

19104

RECRUITING

Hospital of the University of Pennsylvania, Philadelphia

All Listed Sponsors
lead

Darren Schneider, M.D.

OTHER