90
Participants
Start Date
June 30, 2014
Primary Completion Date
November 30, 2014
Study Completion Date
November 30, 2014
Tranexamic Acid - topical
Tranexamic acid is an antifibrinolytic agent that decreases perioperative blood loss, because it inhibits fibrinolysis by competing with lysine molecule in coupling sites in fibrinogen. In this study arm, the drug is administered topically on the wound.
Placebo
100 ml of saline solution administered with anesthesia during 10 minutes
Tranexamic Acid - intravenous
Tranexamic acid is an antifibrinolytic agent that decreases perioperative blood loss, because it inhibits fibrinolysis by competing with lysine molecule in coupling sites in fibrinogen. In this arm, the drug is administered intravenously.
Irmandade da Santa Casa de Misericordia de Sao Paulo
OTHER