NCT02319005 - ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC) | Biotech Hunter

Enrollment

206

Participants

Timeline

Start Date

December 31, 2014

Primary Completion Date

March 30, 2017

Study Completion Date

March 30, 2017

Conditions

Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)Amyloidosis, HereditaryAmyloid Neuropathies, FamilialAmyloid NeuropathiesAmyloidosis, Hereditary, Transthyretin-RelatedFamilial Transthyretin Cardiac Amyloidosis

Interventions

DRUG

Revusiran (ALN-TTRSC)

DRUG

Sterile Normal Saline (0.9% NaCl)

Trial Locations (61)

8003

Clinical Trial Site, Barcelona

8907

Clinical Trial Site, Barcelona

19102

Clinical Trial Site, Philadelphia

19104

Clinical Trial Site, Philadelphia

20037

Clinical Trial Site, Washington D.C.

20422

Clinical Trial Site, Washington D.C.

21201

Clinical Trial Site, Baltimore

21287

Clinical Trial Site, Baltimore

44106

Clinical Trial Site, Cleveland

44195

Clinical Trial Site, Cleveland

60611

Clinical Trial Site, Chicago

60612

Clinical Trial Site, Chicago

60637

Clinical Trial Site, Chicago

Unknown

Clinical Trial Site, Bakersfield

Clinical Trial Site, Beverly Hills

Clinical Trial Site, La Mesa

Clinical Trial Site, Los Angeles

Clinical Trial Site, San Francisco

Clinical Trial Site, Stanford

Clinical Trial Site, Torrance

Clinical Trial Site, Aurora

Clinical Trial Site, Tampa

Clinical Trial Site, Atlanta

Clinical Trial Site, New Orleans

Clinical Trial Site, Detroit

Clinical Trial Site, Rochester

Clinical Trial Site, St Louis

Clinical Trial Site, Newark

Clinical Trial Site, New York

Clinical Trial Site, Rosedale

Clinical Trial Site, The Bronx

Clinical Trial Site, Durham

Clinical Trial Site, Columbus

Clinical Trial Site, Charleston

Clinical Trial Site, Nashville

Clinical Trial Site, Dallas

Clinical Trial Site, Fort Worth

Clinical Trial Site, Houston

Clinical Trial Site, Richmond

Clinical Trial Site, Seattle

Clinical Trial Site, Anderlecht

Clinical Trial Site, Hasselt

Clinical Trial Site, Roeselare

Clinical Trial Site, Toronto

Clinical Trial Site, Bordeaux

Clinical Trial Site, Créteil

Clinical Trial Site, Marseille

Clinical Trial Site, Paris

Clinical Trial Site, Heidelberg

Clinical Trial Site, Münster

Clinical Trial Site, Bologna

Clinical Trial Site, Messina

Clinical Trial Site, Pavia

Clinical Trial Site, Madrid

Clinical Trial Site, Umeå

Clinical Trial Site, Croydon

Clinical Trial Site, London

Clinical Trial Site, Tooting

02111

Clinical Trial Site, Boston

02118

Clinical Trial Site, Boston

02215

Clinical Trial Site, Boston