A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)

PHASE1CompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

December 31, 2014

Primary Completion Date

May 31, 2015

Study Completion Date

November 30, 2015

Conditions
Hypercholesterolemia
Interventions
DRUG

ALN-PCSSC

Single or multiple doses of ALN-PCSSC by subcutaneous (sc) injection

DRUG

Sterile Normal Saline (0.9% NaCl)

calculated volume to match active comparator

Trial Locations (2)

Unknown

Covance Clinical Research Unit, Leeds

Richmond Pharmacology, London

Sponsors
All Listed Sponsors
collaborator

The Medicines Company

INDUSTRY

lead

Alnylam Pharmaceuticals

INDUSTRY