Comparison of Topical and Intravenous Tranexamic Acid in Total Hip Arthroplasty

PHASE3CompletedINTERVENTIONAL
Enrollment

173

Participants

Timeline

Start Date

October 31, 2014

Primary Completion Date

August 31, 2015

Study Completion Date

September 30, 2015

Conditions
Blood Loss
Interventions
DRUG

0.9% sodium chloride

The normal saline solution will be prepared under sterile conditions. In the operation room the sterile bag containing the solution will be given to the scrub nurse. The contents (60 ml) will be emptied in a sterile surgical bowl and the nurse will ask the surgeon to apply the solution before wound closure.The dosage and applying route can also be looked up in doctor's order sheet.

DRUG

tranexamic acid

The Tranexamic Acid solution will be prepared under sterile conditions. In the operation room the sterile bag containing the solution will be given to the scrub nurse. The contents (60 ml) will be emptied in a sterile surgical bowl and the nurse will ask the surgeon to apply the solution before wound closure.The dosage and applying route can also be looked up in doctor's order sheet.

DRUG

tranexamic acid

"The Tranexamic Acid solution will be prepared under sterile conditions. In the operation room the sterile bag containing the solution will be given to the circuit nurse and the circuit nurse will ask the anesthetist to apply the solution intravenously before tourniquet deflation. The dosage and applying route can also be looked up in doctor's order sheet.~60 Milliliters(ml) by irrigation for 3 minutes before wound closure."

Trial Locations (1)

200001

Orthopedic Department of Ruijin hospital, Shanghai

All Listed Sponsors
lead

Shanghai Jiao Tong University School of Medicine

OTHER

NCT02312440 - Comparison of Topical and Intravenous Tranexamic Acid in Total Hip Arthroplasty | Biotech Hunter | Biotech Hunter