Immunomodulation to Optimize Vascularized Composite Allograft Integration for Limb Loss Therapy

PHASE2RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

March 31, 2015

Primary Completion Date

December 31, 2027

Study Completion Date

June 30, 2028

Conditions
Immunosuppression
Interventions
DRUG

Belatacept

This study will also test a new immunosuppressant drug called Nulojix® (belatacept) to see if it is able to prevent rejection in a hand transplant. Nulojix® (belatacept) is approved by the FDA for use in kidney transplants; however, it is investigational in this study.

PROCEDURE

Hand transplant

The purpose of this study is to see if a surgical procedure for transplantation of a hand from a deceased donor can help subjects perform daily living activities better than they are currently able to do.

Trial Locations (1)

27710

RECRUITING

Duke University Medical Center, Durham

All Listed Sponsors
lead

Linda Cendales

OTHER