Neoadjuvant Chemotherapy in Locally Advanced Cervical Cancer Patients

PHASE2CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

September 30, 2013

Primary Completion Date

October 31, 2015

Study Completion Date

October 31, 2015

Conditions
Cancer of Cervix
Interventions
DRUG

gemcitabine

Patients received intravenous 500-1000 ml normal saline and antiemetic medication before chemotherapy. Treatment consisted of intravenous gemcitabine at a dose of 1000 mg/m2 diluted in 500 ml of normal saline administered over 30 minutes mg/m2 diluted in 500 ml of normal saline administered over 30 minutes on days 1 and 8, followed by cisplatin 35 mg/m2 administered over 2 hours on day 1 and 8.

DRUG

cisplatin

35 mg/m2 administered over 2 hours on day 1 and 8.

RADIATION

chemoradiation

external beam radiotherapy concomitant with weekly cisplatin 40mg/m2

Trial Locations (1)

50070550

Instituto de Medicina Integral Fernando Figueira, Recife

All Listed Sponsors
collaborator

Instituto Nacional de Cancer, Brazil

OTHER_GOV

lead

Professor Fernando Figueira Integral Medicine Institute

OTHER

NCT02309658 - Neoadjuvant Chemotherapy in Locally Advanced Cervical Cancer Patients | Biotech Hunter | Biotech Hunter