Investigation of Serotonin Receptor Binding in the Migraine Brain Using Positron Emission Tomography

CompletedOBSERVATIONAL
Enrollment

56

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

August 31, 2017

Study Completion Date

December 31, 2017

Conditions
Migraine Without Aura
Interventions
OTHER

PET scan with 5-HT receptor ligands

Interictal episodic migraine patients and healthy controls will be scanned with a 5-HT1B and a 5-HT4 receptor radioligand. Episodic migraine patients will further be scanned during a cilostazol induced migraine attack and after treatment with sumatriptan. Chronic migraine patients will be scanned with only the 5-HT4 receptor radioligand.

Trial Locations (1)

2600

Danish Headache Center, Glostrup Hospital, Glostrup, Copenhagen

All Listed Sponsors
lead

Danish Headache Center

OTHER

NCT02309606 - Investigation of Serotonin Receptor Binding in the Migraine Brain Using Positron Emission Tomography | Biotech Hunter | Biotech Hunter