18F-Fluoride Assessment of Aortic Bioprosthesis Durability and Outcome

NACompletedINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

September 30, 2018

Study Completion Date

October 30, 2020

Conditions
Heart; Complications, Valve, Prosthesis
Interventions
RADIATION

18F-Fluoride PET-CT

Injection of 18F-Fluoride with target activity 125MBq giving an anticipated radiation exposure of 3mSv CT scanning protocol giving an anticipated radiation exposure of 13mSv

RADIATION

CT calcium score of aortic valve

CT associated with an anticipated radiation exposure of 3mSv (Cohorts 2 and 3 only)

All Listed Sponsors
collaborator

NHS Lothian

OTHER_GOV

collaborator

Cambridge University Hospitals NHS Foundation Trust

OTHER

collaborator

Papworth Hospital NHS Foundation Trust

OTHER_GOV

collaborator

Bichat Hospital

OTHER

lead

University of Edinburgh

OTHER

NCT02304276 - 18F-Fluoride Assessment of Aortic Bioprosthesis Durability and Outcome | Biotech Hunter | Biotech Hunter