Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel

PHASE2CompletedINTERVENTIONAL
Enrollment

47

Participants

Timeline

Start Date

November 30, 2014

Primary Completion Date

July 8, 2016

Study Completion Date

July 8, 2016

Conditions
Acute PainBreast CarcinomaPeripheral Neuropathy
Interventions
DRUG

Minocycline Hydrochloride

Given PO

OTHER

Placebo

Given PO

OTHER

Quality-of-Life Assessment

Ancillary studies

OTHER

Questionnaire Administration

Ancillary studies

Trial Locations (12)

13057

Hematology Oncology Associates of Central New York-East Syracuse, East Syracuse

27103

Novant Health Oncology Specialists, Winston-Salem

48106

Michigan Cancer Research Consortium NCORP, Ann Arbor

51101

Siouxland Regional Cancer Center, Sioux City

54449

Marshfield Clinic, Marshfield

55905

Mayo Clinic, Rochester

56303

Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud

61761

Illinois CancerCare-Community Cancer Center, Normal

61801

Carle Cancer Center, Urbana

68106

Missouri Valley Cancer Consortium, Omaha

93449

PCR Oncology, Pismo Beach

02905

Women and Infants Hospital, Providence

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Academic and Community Cancer Research United

OTHER

NCT02297412 - Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel | Biotech Hunter | Biotech Hunter