The Endurance 1 Trial

PHASE4CompletedINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

November 30, 2014

Primary Completion Date

December 13, 2017

Study Completion Date

March 19, 2018

Conditions
Diabetic Macular Edema
Interventions
PROCEDURE

Focal Laser Treatment

All subjects receiving PRN IVT aflibercept injections will be evaluated for focal laser treatment beginning at week 12 through the end of the study. If the subject meets any of the criteria for focal laser treatment (FLT), fluorescein angiography (FA) will be performed to guide the focal laser treatment. Focal laser treatment and focal laser re-treatment will be administered no more than once every 90 days.

DRUG

aflibercept 2.0 mg

If a subject has recurrent CR-DME they will receive an IVT aflibercept injection

All Listed Sponsors
collaborator

Regeneron Pharmaceuticals

INDUSTRY

lead

Northern California Retina Vitreous Associates

OTHER

NCT02297204 - The Endurance 1 Trial | Biotech Hunter | Biotech Hunter