Nausea in Patients Receiving Hydromorphone vs Oxycodone After Total Hip Replacement Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

August 31, 2012

Primary Completion Date

January 31, 2016

Study Completion Date

January 31, 2016

Conditions
Nausea
Interventions
DRUG

Oxycodone

Patients will receive oxycodone 10mg (5mg if \> 65) every 2 hours based on an equianalgesic dose calculation. As per routine practice, the dose will be titrated according to the patient's pain at the discretion of the Acute Pain Service physician who will not be blinded to group allocation.

DRUG

Hydromorphone

Patients will receive an initial dose of hydromorphone 2mg (1mg if \> 65) every 2 hours as needed based on an equianalgesic dose calculation. As per routine practice, the dose will be titrated according to the patient's pain at the discretion of the Acute Pain Service physician who will not be blinded to group allocation.

Trial Locations (1)

M5T 2S8

Toronto Western Hospital, Toronto

All Listed Sponsors
lead

University Health Network, Toronto

OTHER

NCT02295124 - Nausea in Patients Receiving Hydromorphone vs Oxycodone After Total Hip Replacement Surgery | Biotech Hunter | Biotech Hunter