A Phase 1, Dose-Escalation Trial of PT2385 Tablets In Patients With Advanced Clear Cell Renal Cell Carcinoma (MK-3795-001)

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

November 25, 2014

Primary Completion Date

January 31, 2017

Study Completion Date

November 30, 2026

Conditions
ccRCCRCCKidney CancerClear Cell Renal Cell CarcinomaRenal Cell Carcinoma
Interventions
DRUG

MK-3795

Oral administration

DRUG

Nivolumab

IV infusion

DRUG

Cabozantinib

Oral administration

DRUG

Bezlutifan

Oral administration

Trial Locations (25)

15232

University of Pittsburg Medical Center, Pittsburgh

19111

Fox Chase Cancer Center, Philadelphia

21201

University of Maryland - Greenebaum Cancer Center, Baltimore

22031

Virginia Cancer Specialists, Fairfax

30322

Emory University Winship Cancer Institue, Atlanta

33136

University of Miami - Sylvester Comprehensive Cancer Center, Miami

37203

Tennessee Oncology, Nashville

37232

Vanderbilt Medical Center, Nashville

38138

The West Clinic, Germantown

43210

The Ohio State University, Columbus

44195

Cleveland Clinic, Cleveland

46202

Indiana University Simon Cancer Center, Indianapolis

48201

Barbara Ann Karmanos Cancer Institute, Detroit

53226

Medical College of Wisconsin, Milwaukee

60612

Rush University Medical Center, Chicago

75239

UT Southwestern Medical Center, Dallas

80045

University of Colorado Cancer Center, Aurora

90048

Cedars-Sinai Medical Center, Los Angeles

98104

Swedish Cancer Institute, Seattle

98109

University of Washington, Seattle

06510

Yale School of Medicine, New Haven

02114

Massachusetts General Hospital - Cancer Center, Boston

02215

Beth Israel Deconess Medical Center, Boston

Dana-Farber Cancer Institute, Boston

10019-1147

Mount Sinai Heath System, New York

All Listed Sponsors
lead

Peloton Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

INDUSTRY