12
Participants
Start Date
October 14, 2014
Primary Completion Date
June 28, 2016
Study Completion Date
June 28, 2016
Fludarabine
Patients will receive Fludarabine 25 mg/m\^2/day for 5 days.
Cyclophosphamide
Patients will receive Cyclophosphamide 60 mg/kg/day x 2 days
E6 TCR
On day 0, cells will be infused intravenously (IV) over 20-30 minute (between 1 and 4 days after the last dose of fludarabine)
Aldesleukin
Aldesleukin 720,000 IU/kg IV (based on total body weight) over 15 minutes approximately every 8 hours beginning within 24 hours of cell infusion and continuing for up to 5 days (maximum of 15 doses).
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda
National Cancer Institute (NCI)
NIH