Clinical Trial of Intravitreal Injection of Autologous Bone Marrow Stem Cells in Patients With Retinitis Pigmentosa

PHASE1CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

November 30, 2014

Primary Completion Date

March 31, 2017

Study Completion Date

March 31, 2017

Conditions
Retinitis Pigmentosa
Interventions
BIOLOGICAL

Intravitreal injection of Autologous bone marrow Stem Cell

"We will proceed to the injection of 0.1 ml of the suspension with the autologous MNC of BM avoiding coincide with conjunctival and scleral hole and perpendicular to the sclera.~After the injection, a dry, sterile dressing will be placed to prevent reflux. Immediately, the perception of light, the movement of the central retinal artery, the venous pulse and the color of the papilla will be evaluated. If necessary, anterior chamber paracentesis will be performed.~After injection, the patient will remain with closed eyes and sitting, waiting for cells will be deposited on the bottom of the eyeball and for 3 days will instill tropicamide collyrium every 12 hours."

OTHER

Subconjunctival injection of saline

"In the control eye, will make a subconjunctival injection of 0.1 ml saline. To realize contralateral injection gloves and all surgical materials will change, trying extreme measures of sterility.~After injection, the patient will remain with closed eyes and sitting, waiting for cells will be deposited on the bottom of the eyeball and for 3 days will instill tropicamide collyrium every 12 hours."

Trial Locations (1)

30120

Clinical Universitary Hospital Virgen de la Arrixaca, El Palmar

All Listed Sponsors
collaborator

Spanish National Health System

OTHER

collaborator

Hospital Universitario Virgen de la Arrixaca

OTHER

collaborator

Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia

OTHER

collaborator

Public Health Service, Murcia

OTHER

collaborator

Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca

OTHER

lead

Red de Terapia Celular

INDUSTRY

NCT02280135 - Clinical Trial of Intravitreal Injection of Autologous Bone Marrow Stem Cells in Patients With Retinitis Pigmentosa | Biotech Hunter | Biotech Hunter