PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors

Active, not recruitingOBSERVATIONAL
Enrollment

668

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

July 22, 2022

Study Completion Date

July 24, 2026

Conditions
Sepsis
Interventions
OTHER

Blood collection

Blood will be collected from patient at baseline, day 1, day 4, day 7 and weekly until week 6 as long as the patient is still hospitalized. Blood will also be collected at the one year appointment.

OTHER

Urine collection

Urine will be collected from patient at baseline, day 1, day 4, day 7 and weekly until week 6 as long as the patient is still hospitalized. Urine will also be collected at the one year appointment.

OTHER

Bioimpedance Analysis

The bioimpedance analysis will be performed at baseline, day 14 or discharge from hospitalization, month 3, month 6, and month 12.

OTHER

Cognitive Function Tests

Cognitive function tests will be administered at 3, 6 and 12 months.

OTHER

Quality-of-life Questionnaires

Quality-of-life questionnaires will be administered at baseline, 3, 6 and 12 months.

OTHER

Physical Function Tests

Physical function tests will be administered at baseline, day 14 or discharge from hospital 3, 6 and 12 months.

OTHER

Blood Collection

The healthy volunteer participants will donate a blood sample. These controls will allow the investigators to determine if the values obtained are accurate, reliable, and repeatable.

Trial Locations (1)

32610

UF Health Shands Hospital, Gainesville

All Listed Sponsors
collaborator

National Institute of General Medical Sciences (NIGMS)

NIH

collaborator

American Heart Association

OTHER

lead

University of Florida

OTHER

NCT02276417 - PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors | Biotech Hunter | Biotech Hunter