Impact of Dexmedetomidine on the Post-Operative Cognition Dysfunction(POCD) in Geriatric Patients

PHASE4CompletedINTERVENTIONAL
Enrollment

864

Participants

Timeline

Start Date

October 31, 2014

Primary Completion Date

January 31, 2017

Study Completion Date

February 20, 2017

Conditions
Postoperative ConfusionDelirium
Interventions
DRUG

Dexmedetomidine

0.5μg/kg Dexmedetomidine as initial loading dose is given for 15 minutes before induction of anesthesia, followed by a maintenance infusion of 0.4μg/kg/min and stopped 30 minutes before the surgery over.

DRUG

Saline

0.5μg/kg saline as initial loading dose is given for 15 minutes before induction of anesthesia, followed by a maintenance infusion of 0.4μg/kg/min and stopped 30 minutes before the surgery over.

Trial Locations (13)

Unknown

Anqing Municipal Hospital, Anqing

Affiliated Hospital of Bengbu Medical College, Bengbu

Affiliated Chaohu Hospital of Anhui Medical Hospital, Chaohu

Binhu Hospital of Hefei, Hefei

Second Affiliated Hospital of Anhui Medical University, Hefei

The First Affiliated Hospital of Anhui Medical University, Hefei

The first Hospital of Hefei, Hefei

The Second Hospital of Hefei, Hefei

The Second People's Hospital of Anhui, Hefei

the people's Hospital of Liuan, Liuan

the people's Hospital of Tongling, Tongling

The First Affiliated Hospital of Wannan Medical College, Wuhu

The second People's Hospital of Wuhu, Wuhu

All Listed Sponsors
lead

The First Affiliated Hospital of Anhui Medical University

OTHER

NCT02275182 - Impact of Dexmedetomidine on the Post-Operative Cognition Dysfunction(POCD) in Geriatric Patients | Biotech Hunter | Biotech Hunter