Investigating the Role of the Polyol Pathway in the Central Nervous System

NACompletedINTERVENTIONAL
Enrollment

138

Participants

Timeline

Start Date

February 28, 2015

Primary Completion Date

May 18, 2022

Study Completion Date

May 18, 2022

Conditions
Hyperglycemia
Interventions
OTHER

Brain MRS during hyperglycemic clamp

All patients will undergo brain MRS at baseline and following 2 and 4 hours of hyperglycemia using the clamp technique

OTHER

Analysis of Metabolites in cerebrospinal fluid

All patients will have the option to undergo a lumbar puncture for analysis of metabolites in cerebrospinal fluid

Trial Locations (1)

06519

Yale University, New Haven

All Listed Sponsors
collaborator

American Diabetes Association

OTHER

lead

Yale University

OTHER

NCT02272556 - Investigating the Role of the Polyol Pathway in the Central Nervous System | Biotech Hunter | Biotech Hunter