75
Participants
Start Date
October 31, 2014
Primary Completion Date
January 31, 2018
Study Completion Date
December 31, 2021
Enzalutamide
160 mg (four 40 mg capsules), oral, once daily, 28 days (4 weeks) 6 cycles maximum. Can be taken with or without food.
Abiraterone Acetate
1000 mg (four 250 mg tablets), oral, once daily, 28 days (4 weeks) 6 cycles maximum. No food should be consumed for at least two hours before the dose and for at least one hour after the dose.
Prednisone
5 mg, oral, once daily, 28 days (4 weeks) 6 cycles maximum.Take with food, preferred to be taken in the morning .
Leuprolide Acetate
Either 7.5 mg monthly or 22.5 mg every three months, Intramuscular, monthly or every three months.
Johns Hopkins University, Baltimore
University of Washington, Seattle
Beth Israel Deaconess Medical Center, Boston
Dana-Farber Cancer Institute, Boston
Collaborators (1)
Medivation, Inc.
INDUSTRY
Dana-Farber Cancer Institute
OTHER