The Role of Perioperative Ventilation (Gas Exchange) During Intrabdominal Surgery on Cognitive Function

NACompletedINTERVENTIONAL
Enrollment

109

Participants

Timeline

Start Date

October 31, 2012

Primary Completion Date

August 31, 2016

Study Completion Date

August 31, 2016

Conditions
Response to HyperoxiaHypocapnia
Interventions
PROCEDURE

mechanical ventilation

"Patients subjected to scheduled laparoscopic cholecystectomy were enrolled to the ongoing prospective study and randomized into four groups: 1) normoxia and normocapnia (nO2-nCO2), 2) hyperoxia and normocapnia (hO2-nCO2), 3) normoxia and hypocapnia (nO2-lCO2), and 4) hyperoxia-hypocapnia (hO2-lCO2).~Normoxia PaO2 was referred to PaO2 of 70-140 mm Hg, hyperoxia 150-300 mm Hg, normocapnia PaCO2 of 35-48 mmHg and hypocapnia PaCO2 of 25-35 mmHg."

Trial Locations (1)

163001

City hospital # 1 / Northern State Medical University,, Arkhangelsk

All Listed Sponsors
lead

Northern State Medical University

OTHER

NCT02267031 - The Role of Perioperative Ventilation (Gas Exchange) During Intrabdominal Surgery on Cognitive Function | Biotech Hunter | Biotech Hunter