NCT02265328View on ClinicalTrials.gov

Efficacy of Combination Therapy of Glucocorticoids and Bovine Colostrum in Treatment of Severe Alcoholic Hepatitis.

PHASE2CompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

September 30, 2014

Primary Completion Date

May 31, 2015

Study Completion Date

June 30, 2015

Conditions
Severe Alcoholic Hepatitis in 'Extremis'- Defined by mDF>54
Interventions
DIETARY_SUPPLEMENT

Bovine colostrum

Oral Bovine colostrum 200 ml (20 gram) TDS × 2 months

DIETARY_SUPPLEMENT

Enteral Nutrition

Enteral nutrition: Protein 1.5 gm/kg/day, energy (kcal) 40/kg/day, carbohydrate 67-80%, Fat 20-33%.

OTHER

prednisolone

Oral prednisolone 40mg/day × 4 weeks and tapered to \<40mg/day for next 4 weeks. (If Lilli score \> 0.45 after 7 days, then prednisolone would be stopped)

Trial Locations (1)

141001

Dyanand Medical College and Hospital, Ludhiana

All Listed Sponsors
lead

Dayanand Medical College and Hospital

OTHER

NCT02265328 - Efficacy of Combination Therapy of Glucocorticoids and Bovine Colostrum in Treatment of Severe Alcoholic Hepatitis. | Biotech Hunter | Biotech Hunter