Theophylline and Steroids in Chronic Obstructive Pulmonary Disease (COPD) Study

PHASE4CompletedINTERVENTIONAL
Enrollment

1,670

Participants

Timeline

Start Date

June 30, 2014

Primary Completion Date

May 14, 2018

Study Completion Date

May 14, 2018

Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DRUG

Theophylline

Theophylline is an oral methylxanthine which relaxes smooth muscle through its action as a phosphodiesterase inhibitor

DRUG

Prednisone

Prednisone is an oral glucocorticosteroid which has anti-inflammatory properties

DRUG

Placebo (for prednisone)

"* Arm 1 : Theophylline Placebo 1 tab twice daily and Prednisone placebo 1 tab once daily~* Arm 2 : Theophylline 100mg 1 tab twice daily and Prednisone placebo 1 tab once daily"

DRUG

Placebo (for Theophylline)

One tablet twice daily in arm 1 (theophylline placebo 1 BD + prednisone placebo 1 once daily)

Trial Locations (1)

2000

The George Institute for Global Health, Sydney

All Listed Sponsors
collaborator

National Health and Medical Research Council, Australia

OTHER

lead

The George Institute

OTHER

NCT02261727 - Theophylline and Steroids in Chronic Obstructive Pulmonary Disease (COPD) Study | Biotech Hunter | Biotech Hunter