Cardiovascular Effects of Apelin In Healthy Volunteers

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

November 30, 2014

Primary Completion Date

May 31, 2015

Study Completion Date

May 31, 2015

Conditions
Healthy
Interventions
DRUG

Apelin 1mg subcutaneous

single subcutaneous injection of Apelin 1mg subcutaneous

DRUG

Apelin 1mg intravenous

15 minute intravenous bolus of Apelin 1mg intravenous

DRUG

Apelin 5mg subcutaneous

single subcutaneous injection of Apelin 5mg subcutaneous

DRUG

Apelin 5mg intravenous

15 minute intravenous infusion of Apelin 5mg intravenous

DRUG

Apelin 10 mg subcutaneous

24 hour continuous subcutaneous infusion of Apelin 10 mg subcutaneous

Trial Locations (2)

EH16 4SA

Clinical Research Facility University of Edinburgh, Edinburgh

EH4 2XU

Wellcome Trust Clinical Research Facility. Western General Hospital, Edinburgh

All Listed Sponsors
collaborator

NHS Lothian

OTHER_GOV

lead

University of Edinburgh

OTHER

NCT02259686 - Cardiovascular Effects of Apelin In Healthy Volunteers | Biotech Hunter | Biotech Hunter