Intraductal Meibomian Gland Probing Trial

PHASE4CompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

October 31, 2014

Primary Completion Date

August 31, 2015

Study Completion Date

August 31, 2015

Conditions
Meibomian Gland Dysfunction
Interventions
DRUG

Blephamide

DRUG

GenTeal PM Night-Time

PROCEDURE

Meibomian Gland Probing

For anesthesia, topical 3.5% lidocaine hydrochloride jelly (Akron) was applied directly with sterile cotton-tipped applicator to the lid margin for 3 times every 10 minutes before the procedure. If necessary, 2% lidocaine was injected into the lid margin during the procedure to provide additional comfort. After obtaining adequate anesthesia, the solid stainless steel probes (Maskin® Meibomian Gland Intraductal Probes, Rhein Medical Inc.) were used to probe all the meibomian glands of upper lids of both eyes at the slit lamp. All patients were initially be probed with a 1-mm probe followed by a 2-mm probe for all glands.

PROCEDURE

Sham Meibomian Gland Probing

For anesthesia, topical 3.5% lidocaine hydrochloride jelly (Akron) was applied directly with sterile cotton-tipped applicator to the lid margin for 3 times every 10 minutes before the procedure. If necessary, 2% lidocaine was injected into the lid margin during the procedure to provide additional comfort. The patient's lid margin was touched with the probes without actual probing of the meibomian gland orifices.

Trial Locations (1)

02114

Massachusetts Eye and Ear Infirmary, Boston

All Listed Sponsors
lead

Joseph B. Ciolino, MD

OTHER

NCT02256969 - Intraductal Meibomian Gland Probing Trial | Biotech Hunter | Biotech Hunter