495
Participants
Start Date
November 17, 2014
Primary Completion Date
May 15, 2017
Study Completion Date
August 15, 2022
Pembrolizumab
200 mg intravenous (IV) on Day 1 of each 3-week cycle.
Methotrexate
40 mg/m\^2 IV (may be escalated to 60 mg/m\^2 maximum dose) on Days 1, 8, and 15 of each 3-week cycle
Docetaxel
75 mg/m\^2 IV on Day 1 of each 3- week cycle
Cetuximab
400 mg/m\^2 IV loading dose on Day 1 and 250 mg/m\^2 IV on Days 8 and 15 of Cycle 1, followed by 250 mg/m\^2 on Days 1, 8, and 15 of each subsequent 3-week cycle.
Merck Sharp & Dohme LLC
INDUSTRY