Safety and Efficacy Study of Nab®-Paclitaxel With CC-486 or Nab®-Paclitaxel With Durvalumab, and Nab®-Paclitaxel Monotherapy as Second/Third-line Treatment for Advanced Non-small Cell Lung Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

January 7, 2015

Primary Completion Date

July 17, 2017

Study Completion Date

August 17, 2023

Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG

nab-paclitaxel IV

nab-Paclitaxel intravenous (IV) infusion

DRUG

CC-486

Oral CC-486

DRUG

Duravalumab

Trial Locations (34)

10065

Weill Cornell Medical College - New York - Presbyterian Hospital, New York

17033

Penn State Milton S Hershey Medical Center, Hershey

22927

Local Institution - 663, Großhansdorf

28034

Local Institution - 692, Madrid

28041

Local Institution - 691, Madrid

29010

Local Institution - 694, Málaga

30607

University Cancer and Blood Center, LLC, Athens

33100

Local Institution - 672, Udine

37421

Associates in Oncology and Hematology, Chattanooga

40138

Local Institution - 673, Bologna

43126

Local Institution - 674, Parma

44805

Local Institution - 651, Saint-Herblain

45122

Local Institution - 664, Essen

46014

Local Institution - 697, Valencia

46026

Local Institution - 696, Valencia

59037

Local Institution - 653, Lille

63110

Local Institution - 603, St Louis

74245

Local Institution - 661, Löwenstein

77090

Millennium Oncology, Houston

94143

UCSF Helen Diller Medical Center at Parnassus Heights, San Francisco

94800

Local Institution - 652, Villejuif

06050

Hospital of Central Connecticut Gynecologic Oncology, New Britain

07601

John Theurer Cancer Center at Hackensack University Medical Center, Hackensack

K1H 8L6

Local Institution - 642, Ottawa

H3A 1A1

Local Institution - 641, Montreal

08035

Local Institution - 693, Barcelona

08916

Local Institution - 695, Barcelona

W6 8RF

Local Institution - 630, London

CH63 4JY

Local Institution - 634, Bebington, Wirral

B9 5SS

Local Institution - 633, Birmingham

NW1 2BU

Local Institution - 635, London

M23 9LT

Local Institution - 636, Manchester

NE7 7DN

Local Institution - 632, Newcastle upon Tyne

OX3 7LI

Local Institution - 631, Oxford

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Celgene

INDUSTRY