NCT02249585View on ClinicalTrials.gov

Effects of Neuromuscular Blockade Level and Intra-abdominal Pressure on Surgical Conditions and Cardiopulmonary Responses During Laparoscopic Colon Surgery With the Trendelenburg Position

NACompletedINTERVENTIONAL
Enrollment

131

Participants

Timeline

Start Date

September 30, 2014

Primary Completion Date

October 31, 2016

Study Completion Date

October 31, 2016

Conditions
Cardiac Index
Interventions
DEVICE

Standard abdominal pressure

Abdominal pressure maintained 12mmHg throughout laparoscopic colon surgery

DEVICE

Low abdominal pressure

Abdominal pressure maintained 8mmHg throughout laparoscopic colon surgery

DRUG

Conventional neuromuscular blockade

Anesthesia induction with rocuronium 0.4mg/kg and maintenance with rocuronium 0.15mg/kg to maintain TOF 1-2 twitch

DRUG

Deep neuromuscular blockade

Anesthesia induction with rocuronium 0.8mg/kg → maintenance with rocuronium 0.3mg/kg to maintain PTC 1-2 twitch

Trial Locations (1)

03080

Seoul National University Hospital, Seoul

All Listed Sponsors
lead

Seoul National University Hospital

OTHER

NCT02249585 - Effects of Neuromuscular Blockade Level and Intra-abdominal Pressure on Surgical Conditions and Cardiopulmonary Responses During Laparoscopic Colon Surgery With the Trendelenburg Position | Biotech Hunter | Biotech Hunter